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David R Holmes Selected Research

Contraindications

1/2018Case-Based Discussion Regarding Challenges in Patient Selection and Procedural Planning in Left Atrial Appendage Occlusion.
7/2017The Assessment of the Watchman Device in Patients Unsuitable for Oral Anticoagulation (ASAP-TOO) trial.
7/2016Cost effectiveness of left atrial appendage closure with the Watchman device for atrial fibrillation patients with absolute contraindications to warfarin.
8/2014Mechanical closure devices for atrial fibrillation.
7/2014Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.
3/2012Left atrial appendage closure: a percutaneous transcatheter approach for stroke prevention in atrial fibrillation.
11/2010Atrial fibrillation and stroke management: present and future.

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David R Holmes Research Topics

Disease

82Myocardial Infarction
06/2023 - 05/2002
67Stroke (Strokes)
01/2024 - 08/2002
63Coronary Artery Disease (Coronary Atherosclerosis)
04/2024 - 01/2001
58Hemorrhage
05/2024 - 12/2002
55Thrombosis (Thrombus)
11/2023 - 05/2002
50Atrial Fibrillation
04/2024 - 07/2009
36ST Elevation Myocardial Infarction
01/2021 - 05/2004
25Pathologic Constriction (Stenosis)
03/2021 - 12/2002
21Heart Failure
08/2023 - 05/2002
21Cardiovascular Diseases (Cardiovascular Disease)
01/2015 - 01/2002
18Aortic Valve Stenosis (Aortic Stenosis)
01/2022 - 08/2002
17Diabetes Mellitus
06/2023 - 03/2002
14Cardiogenic Shock
01/2022 - 05/2007
14Acute Coronary Syndrome
11/2017 - 01/2002
13Infarction (Infarctions)
01/2020 - 12/2002
12Ischemic Stroke
11/2023 - 10/2004
11Hypertension (High Blood Pressure)
01/2021 - 01/2005
11Ischemia
10/2020 - 09/2002
10Shock
05/2024 - 01/2003
10Peripheral Arterial Disease
01/2019 - 09/2004
9Transient Ischemic Attack
01/2023 - 06/2006
8Peripheral Vascular Diseases (Peripheral Vascular Disease)
06/2023 - 01/2005
7Chronic Obstructive Pulmonary Disease (COPD)
06/2023 - 11/2012
7Inflammation (Inflammations)
01/2023 - 01/2002
7Heart Arrest (Cardiac Arrest)
01/2022 - 02/2015
7Coronary Stenosis (Coronary Artery Stenosis)
04/2019 - 02/2004
7Coronary Disease (Coronary Heart Disease)
04/2015 - 06/2006
7Stable Angina
04/2009 - 05/2002
6Thromboembolism
01/2021 - 07/2009
6Lung Diseases (Lung Disease)
01/2019 - 11/2014
6Hypercholesterolemia
07/2014 - 01/2002
6Unstable Angina
01/2012 - 01/2002
5Atherosclerosis
10/2023 - 01/2002
5Left Ventricular Dysfunction
04/2017 - 08/2002
5Renal Insufficiency (Renal Failure)
02/2014 - 04/2002
4Acute Kidney Injury (Acute Renal Failure)
01/2020 - 05/2002
4Embolism (Embolus)
12/2019 - 06/2015
4Cardiac Arrhythmias (Arrythmia)
01/2019 - 06/2005
4Chronic Renal Insufficiency
01/2018 - 08/2003
4Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2013 - 12/2004
4Death (Near-Death Experience)
09/2011 - 07/2004
3Hemorrhagic Stroke
01/2022 - 06/2015
3Infections
10/2021 - 11/2019
3Mediastinal Fibrosis
03/2021 - 01/2015
3Vascular Diseases (Vascular Disease)
01/2021 - 02/2011
3Left Ventricular Outflow Obstruction
12/2018 - 12/2004
3Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve)
01/2018 - 01/2017
3Mitral Valve Insufficiency (Mitral Regurgitation)
11/2017 - 03/2017
3Heart Diseases (Heart Disease)
12/2016 - 08/2012
3Epilepsy (Aura)
06/2016 - 08/2008
3Atherosclerotic Plaque (Atheroma)
06/2006 - 01/2002
3Rupture
06/2006 - 12/2002
2Anemia
06/2023 - 09/2017

Drug/Important Bio-Agent (IBA)

29Warfarin (Coumadin)FDA LinkGeneric
01/2024 - 03/2004
27AnticoagulantsIBA
01/2024 - 07/2009
15Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2023 - 03/2004
15MetalsIBA
03/2016 - 07/2004
13Clopidogrel (Plavix)FDA Link
01/2022 - 01/2002
13Sirolimus (Rapamycin)FDA Link
04/2009 - 10/2003
10CreatinineIBA
04/2022 - 03/2002
9thienopyridineIBA
01/2020 - 03/2004
7omega-Chloroacetophenone (Mace)IBA
12/2021 - 01/2002
7Abciximab (ReoPro)FDA Link
07/2010 - 01/2002
6LipidsIBA
12/2021 - 01/2002
6Phenobarbital (Luminal)FDA Link
03/2021 - 05/2003
6Paclitaxel (Taxol)FDA LinkGeneric
10/2019 - 01/2007
5Vitamin KFDA Link
01/2024 - 01/2018
5pexelizumabIBA
07/2011 - 01/2009
4Dihydrotachysterol (AT 10)IBA
06/2023 - 11/2007
4Eptifibatide (Integrilin)FDA Link
05/2008 - 08/2002
4tranilastIBA
01/2006 - 09/2002
4Adenosine (Adenocard)FDA LinkGeneric
04/2004 - 06/2003
3C-Reactive ProteinIBA
06/2023 - 11/2002
32'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2022 - 12/2010
3Insulin (Novolin)FDA Link
10/2021 - 02/2004
3APTIBA
01/2021 - 10/2019
3apixabanIBA
01/2021 - 07/2016
3Oxygen (Dioxygen)IBA
11/2020 - 01/2003
3Endothelins (Endothelin)IBA
09/2008 - 05/2002

Therapy/Procedure

129Percutaneous Coronary Intervention
10/2023 - 01/2001
96Therapeutics
11/2023 - 01/2001
89Stents
10/2023 - 11/2002
60Coronary Artery Bypass (Coronary Artery Bypass Surgery)
04/2024 - 05/2002
34Transcatheter Aortic Valve Replacement
04/2024 - 04/2012
24Drug-Eluting Stents
10/2020 - 01/2006
11Catheters
01/2020 - 11/2002
7Drug Therapy (Chemotherapy)
01/2020 - 05/2003
7Contraindications
01/2018 - 11/2010
6Catheter Ablation
01/2018 - 01/2011
6Blood Transfusion (Blood Transfusions)
01/2018 - 12/2002
5Radiofrequency Ablation
01/2022 - 02/2005
4Lower Body Negative Pressure
05/2024 - 07/2019
4Extracorporeal Membrane Oxygenation
08/2020 - 12/2019
4Length of Stay
01/2019 - 04/2008
4Patient Readmission
11/2017 - 11/2005
4Surgical Instruments (Clip)
03/2017 - 12/2015
4Counterpulsation (External Counterpulsation)
06/2003 - 05/2002
3Thrombectomy
01/2017 - 05/2002
2Embolic Protection Devices
11/2023 - 01/2018
2Artificial Respiration (Mechanical Ventilation)
08/2023 - 01/2020